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"...This insightful book explores the scientific and psychological causes of addiction, as well as the impact on the addicts treated at the Downtown Eastside Vancouver clinic where Mate is a physician. He widens the lens to address the larger societal problem--speaking also to the risks of more "high-status" addictions, such as wealth, power, and sex. He boldly challenges the War on Drugs, proposing a more holistic, constructive set of alternatives....